Figure 2From: Widespread, focal copy number variations (CNV) and whole chromosome aneuploidies in Trypanosoma cruzi strains revealed by array comparative genomic hybridizationGraphical view of proportion of strains displaying CNV for each sequence feature on each chromosome. A sequence feature is defined as either an annotated gene or the un-translated region (UTR) between two genes. CNV criteria were as follows: minimum log2 ratio of signal intensities (test strain/reference) +/- 0.6, minimum number of probes 5, tolerance for extending a CNV 0.1. At the top of each panel is a line drawing representing a chromosome. Vertical bars represent CNV that met the criteria for significance. Vertical bars above the line are amplifications and those below the line are deletions relative to CL-Brener. The height (depth) of the vertical bars is proportional to the number of strains showing that CNV. The vertical bars are colored to indicate strain type (type 1 and type 2) as follows: green, type 1 strains amplification; blue, type 1 strains deletion; maroon, type 2 strains amplification; yellow, type 2 strains deletion. Below each chromosome line drawing is a diagram representing the annotated chromosome. Genes are color coded based on annotation; named genes not belonging to large gene families (dark blue), hypothetical genes (light blue), trans-sialidases (red), mucin associated surface proteins (MASP) (burnt orange), mucins (orange), retrotransposon hotspot (RHS) proteins (green), dispersed gene family 1 (DGF) (gray), surface protease gp63 (purple).Back to article page