Heatmap overview of the circadian pattern in A. aegypti transcriptome. Red areas correspond to higher levels; green areas correspond to lower levels of expression over 2 days of observation. The succession of light and dark periods is marked along the bottom. Each expression profile is assigned one of four phases (marked on the left margin). The algorithm for generation of heatmap of gene expression is explained in Supplemental Figure 1 (see Additional File 1).