Figure 5

Differentially expression of genes annotated to selected GO-terms. A contractile fiber (GO:0043292), B calcium ion binding (GO:0005509), C cartilage development (GO:0051216), D response to wounding (GO:0009611), E cell division (GO:0051301), and F complement activation (GO:0006956). The normalized RPKM values of all significantly differentially expressed genes annotated to the indicated GO terms from standard healing were divided by the corresponding RPKM values from delayed healing. Positive values indicate higher expression levels in standard healing, negative values higher expression levels in delayed healing. A t-test against the null-hypothesis that there is no difference between the healing groups was performed (* p < 0.05, ** p < 0.01).