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Table 1 Overview over differentially expressed genes (R6 animals)

From: Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex

 

total

up

down

 

FC≥2

no FCC

FC≥2

no FCC

FC≥2

no FCC

WT/APP-/-

11

359

2

274

9

85

WT/APLP2-/-

11

1242

6

1142

5

100

WT/APPα/α

15

447

2

250

13

197

APPα/α/APP-/-

2

29

2

29

0

0

  1. The number of significant genes is displayed for all relevant comparisons if at least one probe set identifier of the gene meets the respective criteria. Note that probe sets for App and Aplp2 are not part of the indicated numbers. Numbers indicate significant genes either with fold change criterion (FC≥2, highlighted in bold) or without fold change criterion (no FCC). Note that all animals had been backcrossed for 6 generations to C57BL/6 (R6).
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BMC Genomics

ISSN: 1471-2164

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