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Table 2 Overview over differentially expressed genes: impact of genetic background

From: Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex

 

total

up

down

 

FC≥2

no FCC

FC≥2

no FCC

FC≥2

no FCC

WT(R6)/APLP2(R6)-/-

11

1242

6

1142

5

100

WT(R6)/APLP2(R1)-/-

35

242

19

157

16

85

APLP2(R6)-/-/APLP2(R1)-/-

40

144

19

50

21

94

  1. The number of significant genes is displayed for all relevant comparisons if at least one probe set identifier of the gene meets the respective criteria. Note that probe sets for App and Aplp2 are not part of the indicated numbers. Numbers indicate significant genes either with fold change criterion (FC≥2, highlighted in bold) or without fold change criterion (no FCC). R6: backcrossed to C57BL/6 for 6 generations. R1: backcrossed to C57BL/6 for 1 generation. Note that the comparison WT(R6)/APLP2(R6)-/- is identical to WT/APLP2-/-.
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BMC Genomics

ISSN: 1471-2164

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