TY - JOUR AU - Vedell, Peter T. AU - Svenson, Karen L. AU - Churchill, Gary A. PY - 2011 DA - 2011/03/30 TI - Stochastic variation of transcript abundance in C57BL/6J mice JO - BMC Genomics SP - 167 VL - 12 IS - 1 AB - Transcripts can exhibit significant variation in tissue samples from inbred laboratory mice. We have designed and carried out a microarray experiment to examine transcript variation across samples from adipose, heart, kidney, and liver tissues of C57BL/6J mice and to partition variation into within-mouse and between-mouse components. Within-mouse variance captures variation due to heterogeneity of gene expression within tissues, RNA-extraction, and array processing. Between-mouse variance reflects differences in transcript abundance between genetically identical mice. SN - 1471-2164 UR - https://doi.org/10.1186/1471-2164-12-167 DO - 10.1186/1471-2164-12-167 ID - Vedell2011 ER -