Table 3 Gene Ontology categories significantly enriched with differentially expressed genes
From: Modulation of gene expression in heart and liver of hibernating black bears (Ursus americanus)
GO Category | Total genes on array | Changed genes | Enrichment | FDR |
|---|---|---|---|---|
Biological Process | ||||
HEART | ||||
Translation (GO:0006412) | 319 | 32↑ | 3.334 | <0.001 |
LIVER | ||||
Fatty acid beta-oxidation (GO:0006635) | 22 | 5↑ | 6.805 | 0.036 |
Translation (GO:0006412) | 266 | 28↑ | 3.152 | <0.001 |
Amino acid catabolic process (GO:0009063) | 36 | 12↓ | 10.202 | <0.001 |
Cholesterol metabolic process (GO:0008203) | 34 | 7↓ | 5.951 | <0.001 |
Cellular respiration (GO:0045333) | 47 | 7↓ | 4.559 | 0.024 |
Molecular Function | ||||
HEART | ||||
RNA Binding (GO:0003723) | 455 | 35↑ | 2.500 | <0.001 |
LIVER | ||||
RNA Binding (GO:0003723) | 362 | 28↑ | 2.326 | <0.001 |
Transaminase activity (GO:0008483) | 10 | 5↓ | 15.468 | 0.001 |
Oxidoreductase activity, acting on the aldehyde or oxo group of donors (GO:0016903) | 20 | 6↓ | 9.281 | 0.001 |
Monooxygenase activity (GO:0004497) | 27 | 7↓ | 8.020 | 0.001 |
Electron carrier activity (GO:0009055) | 98 | 11↓ | 3.472 | 0.003 |