TY - JOUR AU - Selga, Elisabet AU - Pérez-Cano, Francisco J. AU - Franch, Àngels AU - Ramírez-Santana, Carolina AU - Rivero, Montserrat AU - Ciudad, Carlos J. AU - Castellote, Cristina AU - Noé, Véronique PY - 2011 DA - 2011/04/11 TI - Gene expression profiles in rat mesenteric lymph nodes upon supplementation with Conjugated Linoleic Acid during gestation and suckling JO - BMC Genomics SP - 182 VL - 12 IS - 1 AB - Diet plays a role on the development of the immune system, and polyunsaturated fatty acids can modulate the expression of a variety of genes. Human milk contains conjugated linoleic acid (CLA), a fatty acid that seems to contribute to immune development. Indeed, recent studies carried out in our group in suckling animals have shown that the immune function is enhanced after feeding them with an 80:20 isomer mix composed of c9,t11 and t10,c12 CLA. However, little work has been done on the effects of CLA on gene expression, and even less regarding immune system development in early life. SN - 1471-2164 UR - https://doi.org/10.1186/1471-2164-12-182 DO - 10.1186/1471-2164-12-182 ID - Selga2011 ER -