Table 1 miRNA loci localized in polymorphic CNV regions
From: Copy number variation of microRNA genes in the human genome
miRNAs localized in 'polymorphic-SMC' CNV regions | ||||||||
|---|---|---|---|---|---|---|---|---|
miRNA ID | miRNA position | dupl. | CNV region position | genotypes | CNV ID | functional relevance | expression (mimiRNA/[18]) | conservation |
mir-1268 | chr15:20014593-20014644 | Â | chr15:19803370-20089386 | 2,3,4,5,6 | 2057 | 1) recurrently deleted in classical Hodgkin's lymphoma [47] | not reported/NA | primates |
mir-1233 | chr15:32607783-32607864 | chr15 | chr15:32487975-32617680 | 0,1,2,3 | 2082 | 1) | not reported/NA | primates |
mir-1972 | chr16:15011679-15011755 | chr16 | chr16:14897364-15016088 | 2,3,4 | 2141 | Â | not reported/NA | primates |
mir-384 | chrX:76056092-76056179 | Â | chrX:76053855-76057477 | 0,1,2 | 2648 | Â | in several tissues/NA | mammals |
miRNAs localized in 'polymorphic-DC' CNV regions | ||||||||
miRNA ID | miRNA position | dupl. | CNV region position | genotypes | CNV ID | functional relevance | expression (mimiRNA/[18]) | conservation |
mir-1977 | chr1:556050-556128 | chrM | chr1:554403-560267 | 2,3,4 | 3.1 | Â | not reported/NA | primates |
mir-1324 | chr3:75762604-75762699 | Â | chr3:75464498-75782745 | 1,2 | 1432.2 | Â | not reported/NA | primates |
mir-548i-2 | chr4:9166887-9167035 | Â | chr4:9117494-9354801 | 1,2 | 1815.3 | Â | not reported/NA | primates |
mir-1275 | chr6:34075727-34075806 | Â | chr6:34071086-34077139 | 1,2 | 2853.1 | 2) upregulated in blood cells of MS patients [41] | not reported/NA | primates |
mir-1302-2 | chr9:20144-20281 | chr1, 15,19 | chr9:485-38531 | 2,3 | 4134_full | Â | not reported/NA | primates |
mir-1233 | chr15:32461562-32461643 | chr15 | chr15:32450046-32662643 | 2,3,4,5 | 6351.3 | 1) | not reported/NA | primates |
mir-1233 | chr15:32607783-32607864 | chr15 | chr15:32450046-32662643 | 2,3,4,5 | 6351.3 | 1) | not reported/NA | primates |
mir-650 | chr22:21495270-21495365 | Â | chr22:20711019-21578950 | 0,1,2 | 8103_full | 1) | in several tissues (mostly ovary and ovary-derived cancers)/high | primates |