Figure 3

Cross-species comparison of TCDD-elicited temporal gene expression responses using cDNA microarrays. (A) The lower half (dark boxes) of the matrix show the number of orthologs represented between pairs of species-specific cDNA microarray platforms. The upper half (grey boxes) of the matrix provides the number of TCDD elicited differentially expressed orthologs between pairs of cell lines. (B) The Venn diagram shows the overlap of all differentially expressed genes (P1(t) > 0.999 and |fold change| > 1.4) from 2,252 possible orthologs represent across all three microarray platforms. Additional files 4, 5, 6 lists the shared responses between pairs of species.