Table 3 List of common genes identified as differentially expressed by TCDD treatment from whole genome Agilent microarray analysis.
Gene Symbol | Gene Name | Homologene ID | Fold changea | |||||
|---|---|---|---|---|---|---|---|---|
Human | Mouse | Rat | ||||||
NQO1 | NAD(P)H dehydrogenase, quinone 1 | 695 | 3.22 | â–² | 4.88 | â–² | 4.82 | â–² |
CCND1 | cyclin D1 | 1334 | 1.57 | â–² | -1.56 | â–¼ | -1.47 | â–¼ |
ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 1633 | 1.74 | â–² | -1.83 | â–¼ | -1.68 | â–¼ |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 9167 | 1.47 | â–² | 7.05 | â–² | 2.91 | â–² |
POC1A | POC1 centriolar protein homolog A | 51460 | -1.64 | â–¼ | -1.67 | â–¼ | -1.57 | â–¼ |
CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 68062 | 13.64 | â–² | 153.52 | â–² | 134.16 | â–² |
GSTA5 | glutathione S-transferase A5 | 74378 | -2.47 | â–¼ | 1.47 | â–² | 5.85 | â–² |
UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 85959 | 2.09 | â–² | 2.24 | â–² | 2.06 | â–² |
MT1E | metallothionein 1E | 108228 | 4.89 | â–² | -1.66 | â–¼ | 2.65 | â–² |