Figure 6
From: Global gene expression profile progression in Gaucher disease mouse models
Time course of expression profiles of pro-inflammatory (A) and anti-inflammatory (B) genes in 9 V/null (white) or 4L (grey) mice. The box plots of fold change (log2) show the median value of fold change of genes in each group (horizontal bars). The upper and lower boundaries of the boxes indicate the 75th and 25th percentile. The whiskers indicate the minimum and maximum of data set. The median fold change in the pro-(A) and anti-(B) inflammatory genes of 9 V/null lung showed a steep increase from 4 to 12 to 28 wk that paralleled those in 9 V/null livers. The expression levels of these same genes in 4L lung and livers were lower and nearly constant over the time course of the analyses.