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Figure 7 | BMC Genomics

Figure 7

From: Global gene expression profile progression in Gaucher disease mouse models

Figure 7

The commonality and uniqueness of significantly differentially expressed genes (A and B) and macrophage activation genes (C and D) in lungs (A and C) and livers (B and D) from 9 V/null and 4L mice. Venn diagrams show the absolute number of differentially expressed genes in 9 V/null or 4L tissues. Among the differentially expressed genes, 729 in lung (A) and 217 in liver (B) were common to 9 V/null and 4L mice. In comparison, the uniquely expressed genes in 9 V/null or 4L lungs were 442 or 646, respectively; and 185 or 189 in 9 V/null or 4L livers. In (C and D) the Venn diagrams represent the number of differentially expressed macrophage activation genes in 9 V/null and 4L lungs (C) and livers (D). Among these genes, 56 in lungs and 13 in livers were found common to 9 V/null and 4L mice. The numbers of uniquely expressed genes in 9 V/null or 4L lungs were 63 or 27, respectively; 13 or 11 in 9 V/null or 4L livers. The expression values of these genes are in Additional file 4.

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