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Table 1 Predominant functional annotations obtained for genes found in selected clusters from Figure 2

From: Expression variability of co-regulated genes differentiates Saccharomyces cerevisiae strains

Cluster1 Functional categories2 TF3 Selection of genes
II Carbohydrate metabolism
Energy reserve metabolic processes
Oxidative phosphorilation
Utilization of amino acids as N source
Glutamate pool management
Amino acid transport
STRE element
Msn2p
Msn4p
Adr1p
Sut1p
DAL2-4, DAL82, DUR1,2, PUT2, GDH2, GDH3, GAP1, UGA4
V Generation of precursor metabolites and energy
Trans-membrane transport
Pleiotropic drug resistance
Amino acid biosynthesis and transport
Adr1p SNF1, JEN1, CAT8, ADR1, MAL31, HXT5, AZR1, PDR10, YOR1, CRS5, TPO2, TPO3, MUP3, STR3, MET32, PUT4
X Sugar transport
Pheromone signaling
Mating
Meiotic recombination
No enrichment MAL11, MPH2, BAR1, STE2, STE6, PRM8, ASG7, FUS1, GPA1, MFA2, STE18, HO, REC102, SPO11
XII Response to toxins
Nitrogen catabolite repression
No enrichment AAD4, AAD6, AAD14, AAD16, ADH7, DAL80
XIII Sterol metabolism
Thiamine biosynthesis
Cell wall composition
Iron homeostasis
Pleiotropic drug resistance
Mot3p
Nrg1p
Aft2p
Cin5p
DAN1-DAN4, TIR4, PAU1-PAU6, ARE1, HES1, FET4, PDR11
  1. 1Clusters highlighted in Figure 2A; 2Derived from GO term enrichment analysis (p-value < 0.05); 3Obtained from enrichment analysis for transcription factor binding site in the gene promoter region (p-value < 0.05, adjusted with Bonferroni multiple tests correction).