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Table 1 Discovery set genes showing QPCR validated transcriptional differences between WT and KO (Gpr54 or Kiss1)

From: The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent

  GKO vs WT KKO vs WT
Gene Target FC (95%CI) Direction FC (95%CI) Direction
Abca8a 1.85 (1.33-2.59) Up 1.97 (1.33-2.90) Up
Esr1 1.62 (1.37-1.92) Up 1.54 (1.32-1.78) Up
Kiss1 14.03 (10.86-18.11) Up N.A. N.A.
Mmp2 1.51 (1.18-1.94) Up n.s. n.s.
Npas4 2.60 (2.09-3.25) Up n.s. n.s.
Lrdd n.s. n.s. 1.80 (1.29-2.51) Up
Tmem144 n.s. n.s. 2.61 (2.21-3.08) Up
  1. FC = fold change, CI = confidence interval, n.s. = not significant, N.A. = not applicable. GKO = GPR54 knockout, KKO = Kisspeptin knockout.