Figure 4

The SIMBAL heat map for gi|284167095 from Haloterrigena turkmenica , a Zn-dependent protein from family TIGR03989. SIMBAL training sets contained 590 sequences in the TRUE partition and 3620 in the FALSE partition after making the sets non-redundant to no more than 80% sequence identity. The apex score of 30.1 nears that of highest local score, consistent with the ability of TIGR03989 to identify large numbers of members found exclusively in mycofactocin-producing species. Interesting features include extended cool (blue and green) regions such as the N-terminal region of about 80 residues, which contains regions well conserved among Zn-dependent alcohol dehydrogenases yet apparently poorly predictive for whether or not a matching protein's genome of origin contains the mycofactocin cluster.