Table 3 Comparison of adipocyte-genes between bone marrow and epididymal adipocytes
From: Characterization of age-related gene expression profiling in bone marrow and epididymal adipocytes
Symbol | Entrez Gene Name | 6-month | 14-month | 18-month |
|---|---|---|---|---|
Increased expression in bone marrow | Â | Â | Â | |
LEPR | leptin receptor | 19.7 | 7.4 | 16.4 |
OSM | oncostatin M | 18.1 | 20.1 | 11.4 |
RGS2 | regulator of G-protein signaling 2, 24kDa | 15.3 | 15.8 | 8.9 |
SFRP4 | secreted frizzled-related protein 4 | 14.8 | 1.8 | 6.6 |
ABCB4 | ATP-binding cassette, sub-family B, member 4 | 10.7 | 6.9 | 7.4 |
TNFRSF1β | CD120b | 6.6 | 4.3 | 8.3 |
TNFα | tumor necrosis factor α | 5.0 | 26.3 | 7.2 |
100001G20RIK | RIKEN cDNA 1100001G20 gene, Wdnm1-like | 4.2 | 4.5 | 3.0 |
UCP2 | uncoupling protein 2 | 4.0 | 2.1 | 3.7 |
LPIN2 | lipin 2 | 4.0 | 3.9 | 5.6 |
TGFB1 | transforming growth factor, beta 1 | 3.9 | 2.5 | 3.8 |
GPR109A | G protein-coupled receptor 109A | 3.7 | 33.6 | 2.3 |
C/EBPβ | CCAAT/enhancer binding protein beta | 2.3 | 6.8 | 1.3 |
IL6 | interleukin 6 | -1.1* | 8.8 | 2.8 |
Decreased expression in bone marrow | Â | Â | Â | |
LEP | leptin | -152.5 | -300.1 | -454.4 |
CFD | complement factor D (adipsin) | -138.2 | -115.9 | -107.1 |
RETN | resistin | -114.7 | -87.4 | -153.7 |
CDO1 | cysteine dioxygenase, type I | -106.9 | -132.3 | -192.1 |
PLIN1 | perilipin 1 | -100.6 | -85.1 | -106.5 |
ERPINE1 | plasminogen activator inhibitor type 1 | -60.9 | -7.0 | -19.0 |
FASN | fatty acid synthase | -32.9 | -28.5 | -43.5 |
ADIPOQ | adiponectin | -26.4 | -35.3 | -41.2 |
FABP4 | fatty acid binding protein 4, adipocyte | -23.2 | -27.0 | -41.3 |
LIPE | lipase, hormone-sensitive | -21.9 | -15.2 | -26.8 |
LPL | lipoprotein lipase | -21.8 | -18.8 | -23.9 |
KLB | klotho beta | -21.1 | -12.9 | -29.6 |
ACOX1 | acyl-Coenzyme A oxidase 1, palmitoyl | -16.5 | -10.2 | -12.8 |
FGFR1 | fibroblast growth factor receptor 1 | -12.2 | -11.4 | -10.2 |
SLC2A4 | glucose transporter member 4 | -10.2 | -9.5 | -9.2 |
C/EBPα | CCAAT/enhancer binding protein, alpha | -6.7 | -8.7 | -11.2 |
PPARγ | peroxisome proliferator-activated receptor gamma | -5.9 | -4.8 | -10.3 |
IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -5.1 | -4.7 | -6.4 |
ADIPOR2 | adiponectin receptor 2 | -4.7 | -4.0 | -4.7 |