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Table 6 Age-related fold changes in genes involved in lipolysis

From: Characterization of age-related gene expression profiling in bone marrow and epididymal adipocytes

   Bone marrow Epididymal
Symbol Entrez Gene Name 14M 18M 14M 18M
ABHD5 αβ hydrolase domain containing 5 -1.12 -1.26 -1.97 1.04
ACACB acetyl-CoA carboxylase beta -1.40 -1.14 -2.22 -1.31
ADRB2 adrenergic, beta-2-, receptor, surface 1.22 1.49 -1.37 -2.04
C3 complement component 3 -1.07 -1.23 2.16 -1.11
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -1.38 -1.53 -1.60 -1.15
FOXO1 forkhead box O1 1.99 1.17 -1.42 -1.44
GPR109A G protein-coupled receptor 109A -1.29 -3.99 -10.52 -2.20
NR4A1 nuclear receptor subfamily 4, group A, member 1 2.53 1.11 -4.03 -4.62
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 1.07 1.05 1.54 -1.21
PDE3B phosphodiesterase 3B, cGMP-inhibited 1.57 1.25 -1.99 -1.32
PLIN1 perilipin 1 -1.24 -1.21 -1.36 1.04
PNPLA2 patatin-like phospholipase domain containing 2 -1.03 -1.43 -1.39 -1.21
TNF tumor necrosis factor 2.37 -1.38 -2.36 -2.12
  1. The list includes age-related fold change in genes involved in lipolysis in bone marrow and epididymal adipocytes. The set of regulated genes was selected according to the IPA knowledge-base. The 14-month (14M) and 18-month-old (18M) were compared to 6-month-old. The significance of differences was measured by two-way ANOVA. The significance of differences was estimated by a Benjamini-Hochberg corrected p value (p < 0.01).