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Table 3 S. mansoni ePKinome annotation improved by phylogenomics

From: Eukaryotic Protein Kinases (ePKs) of the Helminth Parasite Schistosoma mansoni

After phylogenetic analysis

Modifications

Number of changes

% of S. mansoni ePKinome

Change group classification

14

5,55%

Change family classification

18

7,14%

Add subfamily

61

24,20%

Classification of unknown proteins

11

3,96%

Total of changes

104

40,85%

  1. Through phylogenetic analysis, we have improved the functional annotation of 40% of S. mansoni ePKs by changing protein classification at the group and family levels, assigning subfamilies, and classifying proteins without any previous classification.