Figure 2

Hierarchical clustering of differently expressed transcripts in hypothalamic cells. The color strap indicates degrees of up- (red) and down- (green) regulation of gene expression. The dendrogram at the right shows the grouping of genes according to their similarity in expression profiles. A value of zero indicates that the genes have the same regulation profile. The transfected purified (GFP+) cell population was compared to the transfected non-purified (GFP+/-) or non-transfected (NT) cell populations in a log₂-based threshold. The data correspond to transcripts enriched in the GFP+ cells only. The gene hierarchical cluster was performed using the multiple group analysis and the CLARA algorithm as described [54].