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Table 3 Dissimilar genes between E. coli and S. aureus infections in cattle

From: Strengthening insights into host responses to mastitis infection in ruminants by combining heterogeneous microarray data sources

Gene Gene Name E. coli shrunken centroid S. aureus shrunken centroid
ABCG2 ATP-binding cassette, sub-family G WHITE, member 2 -1.007 0.671
IDH1 Isocitrate dehydrogenase 1 NADP+, soluble -0.929 0.619
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 lysophosphatidic acid acyltransferase, alpha -0.894 0.596
PCGF1 Polycomb group ring finger 1 -0.795 0.53
GALNTL4 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4 -0.52 0.346
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -0.496 0.33
TMEM164 Transmembrane protein 164 -0.42 0.28
RHOF Ras homolog gene family, member F -0.391 0.261
MFSD4 Major facilitator superfamily domain containing 4 -0.263 0.175
DGCR2 DiGeorge syndrome critical region gene 2 -0.217 0.145
FEZ1 Fasciculation and elongation protein zeta 1 zygin I -0.204 0.136
PAOX Polyamine oxidase exo-N4-amino -0.154 0.103
PMEPA1 Prostate transmembrane protein, androgen induced 1 -0.106 0.07
HIGD1B HIG1 hypoxia inducible domain family, member 1B -0.134 0.089
DNAJC12 DnaJ Hsp40 homolog, subfamily C, member 12 -0.132 0.088
VWF Von Willebrand factor -0.131 0.088
KIAA1467 KIAA1467 -0.131 0.087
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 -0.068 0.046
IGFBP5 Insulin-like growth factor binding protein 5 -0.06 0.04
SCP2 Sterol carrier protein 2 -0.018 0.012
NPAL2 NIPA-like domain containing 2 -0.009 0.006
LRRN3 Leucine rich repeat neuronal 3 0.732 -0.488
FKBP5 FK506 binding protein 5 0.7 -0.466
SLC38A7 Solute carrier family 38, member 7 0.641 -0.427
HSPD1 Heat shock 60 kDa protein 1 chaperonin 0.56 -0.373
GLUL Glutamate-ammonia ligase glutamine synthetase 0.352 -0.235
CSDA Cold shock domain protein A 0.174 -0.116
INO80E INO80 complex subunit E 0.142 -0.095
SAT1 Spermidine/spermine N1-acetyltransferase 1 0.118 -0.079
PHB Prohibitin 0.075 -0.05
STAT3 Signal transducer and activator of transcription 3 acute-phase response factor 0.061 -0.04
MAX MYC associated factor X 0.051 -0.034
BTG1 B-cell translocation gene 1, anti-proliferative 0.033 -0.022
LCN2 Lipocalin 2 0.024 -0.016
  1. List of the 34 most dissimilarly regulated genes identified with the PAMR software, showing opposite fold change responses during E. coli and S. aureus infections in cattle in vivo (experiment 1A, B, and C). For each gene, the PAMR shrunken centroid values (using a threshold parameter of 3.77) for the E. coli and the S. aureus experiments are reported. Twenty-one of the listed genes were up-regulated during infection with S. aureus, while 13 were up-regulated during E. coli infection.