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Table 4 Expression of the genes encoding the transcriptional activators for switching on production of the CDA, Red and Act biosynthetic clusters is induced following exposure to vancomycin, bacitracin and moenomycin.

From: Genome-wide dynamics of a bacterial response to antibiotics that target the cell envelope

Antibiotic cluster Activator gene vancomycin Fold-change increase in expression in the 90 min sample1
   Vancomycin Bacitracin Moenomycin
CDA cdaR (SCO3217) 5.4 2.4 1.5
Act actII-ORF4 (SCO5085) 2.8 1.6 1.5
Red redD (SCO5877) 11.4 4.4 2.1
Red redZ (SCO5881) 5.7 3.6 NA
  1. 1NA = the gene was not present in the list of significantly differently expressed genes in Additional files 1, 2 and 3.