Skip to main content

Table 3 Enriched TFBSs.

From: Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes

TF Description Cromo-some P-Value Binding motif Strand
E2F1 E2F transcription factor 1 chr20 9.3*10-18 [C/t][C/a][G/c]C[c/a][C/g][G/c][C/T][G/c]A -
RUNX1 runt-related transcription factor 1 chr21 4.0*10-18 [C/a/t][T/a/g][G/C]{A}[G/c]{A}T[C/A][G][C/a/t/g] +
paired box 2 chr10 8.4*10-18 [A/g][A/g]A[C/T/a][T/g/a][T/c][C/t][C/g][C/a] +
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) chr17 8.4*10-17 GAA[A/T][C/T]G[C/T][C/g/t][A/T][C/T/g] +
  1. Binding motifs have been represented using the IUPAC nomenclature and incorporating lower case for low frequency bases.