Figure 2
From: Genome-wide patterns of promoter sharing and co-expression in bovine skeletal muscle
Linking co-expression and co-regulation. (A) Percentage increase of co-expression correlations between pairs of TFs as a function of the number of common TFBS and for absolute correlations (red bars) and positive correlations (green bars); (B) Percentage increase (black circles trend) and cumulative frequency (red triangles trend) of co-expression correlations between pairs of TFs as a function of the number of common targets and for absolute correlations; (C) Number of common TFBS as a function of the co-expression correlation for a pair of genes. Observed (black) and naive expectation (red); (D) Target co-expression: Ratio of the average absolute correlation between a TF and its TG over the average absolute correlation between a TF and all genes in the dataset, and as a function of the number of TGs (x-axis). Values on y-axis above one signify the expression of a TF is more correlated with its TGs than with all the genes. Highlighted in red are the 94 TFs for which the average absolute correlation with their TGs is above average.