Figure 3

DS-DMRs: Heat Map of methyation signal in the Hoxa gene region during development in different tissues. A heat map was constructed based on the NimbleGen P scores of probes, in the Hoxa gene cluster region. Probes included in the heat map either have a P score ≥2 for both of the duplicated samples or at least one tissue/developmental stage or fall into the promoter region of a Hoxa gene. Each row of the color tiles in the heat map represents a NimbleGen probe, while each column represents a sample. The tissue name is labeled at the bottom, while the developmental stage is indicated at the top. The labeled arrows at the right side indicate the position of the TSS and direction of the Hoxa gene transcription. The T-DMRs and DS-DMRs methylation peaks corresponding to those in Additional file 14b are indicated by the numbers on the left side.