Figure 1From: Genome-wide profiling of G protein-coupled receptors in cerebellar granule neurons using high-throughput, real-time PCRDistribution of the abundance of transcripts encoding G protein-coupled receptors in differentiated cerebellar granule neurons. Transcripts encoding 382 GPCRs were quantified in cerebellar granule neurons grown in vitro for 7 days (DIV 7) using real-time PCR. The distribution of transcript abundance was plotted with intervals equal to the interquartile range (IQR; the difference between the first and third quartile). The majority (298) of GPCRs are expressed at very low levels, i.e. between median - 0.5 IQR and median + 3.5 IQR. A population of 46 GPCRs displays intermediate expression levels (median + 4.5 IQR to median + 9.5 IQR), and 38 GPCRs are expressed above median + 10 IQR. The medium to high population of GPCRs likely corresponds to the physiologically most relevant GPCRs.Back to article page