PCA plots (after ANOVA p < 0.01) of the apolar fraction of HepG2 analyzed by 1H NMR and pre-processed and aligned using a program developed in-house. A: Spheres with the same colour are technical replicates of the same sample per passage number. DMSO30: green; TCDD30: red; DMSO7: lila; TCDD7: yellow; DMSO11b: light blue; TCDD11b: dark blue; DMSO17: orange; TCDD17: purple; DMSO11b: light green; TCDD11b: white. B: Samples re-grouped with regard to treatment (irrespective of passage number). DMSO: green; TCDD: red.