Clinical signs | Cohen Syndrome (%)†| TNS (%) |
---|
typical facies | 81* | 43 |
slender extremities | 91 | 86 |
mental retardation | 99 | 43 |
microcephaly | 53 | 71 |
infantile hypotonia | 86 | 71 |
developmental delay | 81 | 86 |
delayed puberty | 41 | 86 |
short stature | 47 | 60‡ |
truncal obesity | 65 | 0 |
neutropenia | 75§ | 100 |
myopia | 44 | n/a |
cataracts | 64 | n/a |
- n/a - not available
- * average for clinical signs: short philtrum, high narrow palate, prominent nasal bridge and prominent central upper incisors
- †Data summarised from Taban et al. [23] where the number of individuals for each category varies depending on what has been reported in the literature
- ‡ out of five dogs as two died before reaching maturity
- § data summarised from Hennies et al. [24]; Kivitie-Kallio and Norio [25]; Chandler et al. [26]; Kolehmainen et al. [15]; Bugiani et al. [27]; Kivitie-Kallio et al. [12]; and Seifert et al. [14].