Network Property
|
Valuesa
|
---|
Nodes
|
1477
|
Edges
|
49997
|
Scale-free topologyb
|
0.829
|
Mean shortest path lengthc
|
3.1
|
Network diameterd
|
10
|
Mean connectivitye
|
17.3
|
Centralizationf
|
0.648
|
Heterogeneityf
|
1.91
|
Clustering coefficientg
|
0.811
|
- aGlobal gene networks were generated via Weighted Gene Correlation Network Analysis (WGCNA) [37] and network properties were calculated using the Network Analyzer plugin [51] that was developed for Cytoscape [50].
- b Identifies networks that have a topology similar to other biological networks and ranges from 0 - 1 [37].
- cAverage shortest path length between two nodes.
- dMaximum distance amongst all distances calculated between two nodes.
- eAverage number of connections made by each node.
- fNetwork topology that resembles a star has a centralization of 1 and decentralized networks have a centralization of 0. Heterogeneity reflects the tendency of a network to contain hub nodes [119].
- gThe average clustering coefficient can be used to measure whether the network exhibits modular organization [120].