Table 2 Enhanced Gene Classes in An. gambiae Chemosensory Tissues
| Â | Â | Â | Â | enhanced >2x | Â | Â | |
|---|---|---|---|---|---|---|---|
gene class | PfamA | PfamA description | # An. gambiae | FA | MA | FP | MP |
7tm Receptor | PF00001 | 7tm receptor (rhodopsin family) | 84 | 28 | 20 | 18 | 14 |
7tm Receptor | PF02949 | 7tm Odorant receptor (Or) | 78 | 56 | 31 | 3 | 3 |
7tm Receptor | PF08395 | 7tm Chemosensory receptor (Gr) | 52 | 1 | 4 | 3 | 4 |
7tm Receptor | PF00002 | 7tm receptor (Secretin family) | 11 | 2 | 1 | 0 | 2 |
7tm Receptor | PF00003 | 7tm sweet-taste receptor of 3 GCPR | 7 | 4 | 5 | 2 | 1 |
lipophilic carrier | PF01395 | PBP/GOBP family | 62 | 18 | 17 | 6 | 4 |
lipophilic carrier | PF00650 | CRAL/TRIO domain | 43 | 17 | 9 | 17 | 16 |
lipophilic carrier | PF06585 | Haemolymph juvenile hormone bind. (JHBP) | 24 | 10 | 5 | 15 | 9 |
lipophilic carrier | PF00188 | Cysteine-rich secretory protein family | 20 | 7 | 2 | 9 | 7 |
lipophilic carrier | PF03392 | Insect pheromone-bind. family, A10/OS-D | 7 | 2 | 2 | 4 | 1 |
CD36/SNMP | PF01130 | CD36 family | 14 | 5 | 1 | 7 | 5 |
channel/transporter | PF07690 | Major Facilitator Superfamily | 65 | 21 | 16 | 16 | 13 |
channel/transporter | PF00083 | Sugar (and other) transporter | 49 | 7 | 4 | 7 | 8 |
channel/transporter | PF00060 | Ligand-gated ion channel | 29 | 22 | 20 | 5 | 3 |
channel/transporter | PF00520 | Ion transport protein | 27 | 15 | 10 | 9 | 3 |
channel/transporter | PF02931 | Neurotrans.-gated ion-channel ligand bind. | 24 | 10 | 6 | 4 | 0 |
channel/transporter | PF00858 | Amiloride-sensitive sodium channel | 23 | 5 | 2 | 1 | 1 |
channel/transporter | PF01061 | ABC-2 type transporter | 19 | 10 | 4 | 12 | 11 |
channel/transporter | PF00005 | ABC transporter | 18 | 4 | 3 | 5 | 2 |
channel/transporter | PF00664 | ABC transporter transmemb. | 15 | 4 | 2 | 2 | 4 |
channel/transporter | PF07885 | Ion channel | 9 | 3 | 3 | 1 | 1 |
biotransformation | PF00067 | Cytochrome P450 | 113 | 30 | 19 | 34 | 24 |
biotransformation | PF00135 | Carboxylesterase | 50 | 15 | 13 | 14 | 14 |
biotransformation | PF00043 | Glutathione S-transferase, C-term. | 18 | 6 | 1 | 4 | 1 |
biotransformation | PF02798 | Glutathione S-transferase, N-term. | 17 | 5 | 3 | 4 | 3 |
transcription factor | PF00096 | Zinc finger, C2H2 type | 114 | 21 | 50 | 21 | 24 |
transcription factor | PF00046 | Homeobox domain | 76 | 17 | 19 | 14 | 13 |
transcription factor | PF00651 | BTB/POZ domain | 54 | 17 | 26 | 5 | 7 |
transcription factor | PF00010 | Helix-loop-helix DNA-binding | 41 | 6 | 6 | 5 | 6 |
transcription factor | PF00250 | Fork head domain | 19 | 6 | 8 | 3 | 4 |
transcription factor | PF07716 | Basic region leucine zipper | 14 | 3 | 4 | 1 | 3 |
transcription factor | PF00292 | \Paired box\ domain | 10 | 3 | 5 | 3 | 3 |
transcription factor | PF00907 | T-box | 11 | 8 | 6 | 8 | 5 |
transcription factor | PF00170 | bZIP transcription factor | 8 | 3 | 3 | 2 | 2 |
transcription factor | PF00157 | Pou domain - N-terminal to homeobox | 4 | 2 | 3 | 3 | 1 |