Figure 4
From: MicroRNA profiling of rhesus macaque embryonic stem cells
The degree of genes regulated by miRNAs is negatively correlated with their evolutionary rate in rESCs. (A): The correlation coefficient (r = -0.564 with P = 0.018 based on Pearson's correlation) between dN/dS ratios and degrees of genes regulated by miRNAs in rESCs; (B): The correlation coefficient (r = -0.556 with P = 0.039 based on Pearson's correlation) between dN/dS ratios and degrees with normalization of 3'UTR length per 1 kb; (C): The correlation coefficient (r = -0.533 with P = 0.019 based on Pearson's correlation) between dN/dS ratios and degrees with normalization of 3'UTR length per 2 kb; (D): The degree of miRNAs and their targets in the random network is significantly lower (p < 2.2e-16 with a Wilcoxon rank sum test) compared with those in the MT network.