Table 2 Significantly altered mRNA and proteins related to carbohydrate metabolism
| Â | Transcriptomics | Proteomics | ||
|---|---|---|---|---|
Glycogenesis | Adj. p-value | Fold change | Adj. p-value | Fold change |
Glucokinase (Gck) | 4.84E-03 | 1.8 | Â | Â |
Glucan (1,4-alpha-), branching enzyme 1 (Gbe1) | 3.03E-03 | 2.3 | 2.98E-05 | 1.5 |
Glycogenolysis | Â | Â | Â | Â |
Amylo-1,6-glucosidase, 4-alpha-glucanotransferase (Agl) | 6.05E-03 | 1.8 | Â | Â |
Protein phosphatase 1, regulatory (inhibitor) subunit 2 (Ppp1r2) | 4.00E-03 | 1.4 | Â | Â |
Glycogen phosphorylase, liver form (Pygl) | Â | Â | 1.41E-03 | 1.2 |
Glycolysis | Â | Â | Â | Â |
Glucokinase (Gck) | 4.84E-03 | 1.8 | Â | Â |
Aldolase C, fructose-bisphosphate (Aldoc) | 8.48E-03 | 1.9 | Â | Â |
Alpha-enolase (Eno1) | Â | Â | 1.62E-03 | 1.1 |
Pyruvate kinase, liver (Pklr) | Â | Â | 3.28E-05 | 1.5 |
Fructose-bisphosphate aldolase B (Aldob) | Â | Â | 2.59E-03 | 1.2 |
Glucose-6-phosphate isomerase (Gpi) | Â | Â | 6.90E-05 | 1.2 |
Glyceraldehyde-3-phosphate dehydrogenase (Gapdh) | Â | Â | 1.10E-03 | -1.2 |
Gluconeogenesis | Â | Â | Â | Â |
Fructose bisphosphatase 1 (Fbp1) | 3.35E-03 | -1.9 | 4.26E-06 | -1.4 |
Phosphoenolpyruvate carboxykinase 1, cytosolic (Pck1) | 3.22E-03 | -10.2 | Â | Â |
TCA Cycle-related | Â | Â | Â | Â |
Pyruvate dehydrogenase complex component E2 (Dlat) | 4.48E-03 | 1.8 | Â | Â |
Pyruvate dehydrogenase kinase, isoenzyme 1 (Pdk1) | 7.73E-03 | 2.0 | Â | Â |
Pyruvate dehyrogenase phosphatase catalytic subunit 2 (Pdp2) | 6.96E-03 | -1.4 | Â | Â |
Fumarate hydratase (Fh1) | 2.02E-03 | -1.6 | 3.78E-03 | -1.2 |
Succinate dehydrogenase flavoprotein subunit, mitochondrial (Sdha) | 3.05E-03 | -1.3 | Â | Â |
2-oxoglutarate dehydrogenase complex component E2 (Dlst) | Â | Â | 2.53E-03 | -1.2 |