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Figure 1 | BMC Genomics

Figure 1

From: Gene expression profiling of rat spermatogonia and Sertoli cells reveals signaling pathways from stem cells to niche and testicular cancer cells to surrounding stroma

Figure 1

Proliferation and differentiation of germ cells and Sertoli cells of young rats at two different stages of development. (A) Schematic presentation of differentiation stages of germ cells (Spermatogonia As, Apr, Aal, A1, A2, A4, and B, and Spermatocytes (Spcy)) and Sertoli cells (blue shaded area) which surround the germ cells of pre-pubertal (9 dpp) and pubertal (22 dpp) rats. Blood-testis barrier (BTB) formed by Seroli cells at 9 dpp is indicated. (B) Sections of seminiferous tubules were stained with hematoxylin (HE) and antibodies against proliferating cell nuclear antigen (PCNA) to confirm proliferation of all spermatogonia at 9 dpp, but few at 22 dpp.

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