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Table 1 The most up-regulated genes found in type A spermatogonia and Sertoli cells at 9dpp.

From: Gene expression profiling of rat spermatogonia and Sertoli cells reveals signaling pathways from stem cells to niche and testicular cancer cells to surrounding stroma

 

Mitotic Spermatogonia type A at 9dpp

Immature Sertoli cells at 9dpp

Cell adhesion, ligand, ECM

(12) Alcam, Bdnf, Ctgf, Cyr61, Daf1, Hbegf,

(19) Asam, Boc*, Cdh11, Cdh22, Col4a1*, Itgav*, Mdk, Pdgfc, Pvr, Tpbg, Vasn*, Col4a2*, Cthrc1, Cxcl13, Fbn1, Gpc1, Madcam1, Ncam1, Npy, Pap, Pap3, Sfrp1, Spp1, Thbd, Torid

Cytoskeleton

(5) Actn1, Coro1a, Mig12, Nef3, Sprr1*

(8) Dbn1, Mybpc3*, Nes, Pdlim2, Pdlim3, Tmod1, Trim2*, Tubb2b*

Cell cycle, Apoptosis

(6) Gadd45a, Gadd45b*, Gadd45g*, Myc, Plk2, Tpd52l1*,

(3) Cdkn2a, Cdkn2b, Mtsg1

Intracellular membranes, Trafficking

(3) Mal2, Scrn1, Snx7*

(2) Ech1, Tmem98*

Metabolism

(10) Akr1c18, Gls, Gpx1, Lpl, Prkaa1, Qpct*, Rfk*, Sms*,Txnip, Ugcg

(12) Ddah2, Cbr3*, Cox6a2, Cp, Crym, Dio3, Gpx7*, Gsta2, Idh2, Mgst2*, Pygl, SelM*

RNA Splicing, translation

(2) Rpl13, Rpl37

(1) Hspb1

Receptors, channels, transporters

(11) Cd7*, Edn1, F2r, Gnai1, Lgr4, Nritp, P2ry1, Slc4a4, Slc6a15, Slc7a3, Slc16a6

(11) Gpr83*, Kdr, Ntrk1, Scn3b, Scn4b, Slc15a2, Slc26a3, Smstr28*, Sntg2*, Tacstd2, Trfr2*

Signal transduction

(13) Anxa3, Arhgap18*, Arhgap21*, Dusp1, Hipk3, Ppp1r14c, Ptpre, Rnd3, Sdpr, Sgk, Tm4sf12, Trib2*, Trib3

(9) Arhgef4*, Cpne8, Ptpns1, Ltbp2, Rerg*, Rrad, S100a3, S100a5*, Smoc2*

Transcription, chromatin

(11) Anp32a, Atf3, Ets1, Fosl1, Hes1, Mycn, Nap1l3, Parp8*, Rb1, Tle4, Zfp469*

(9) Giot1, Lmcd1*, Nr4a1, Nupr1, Rgc32, Sox18*, Tead2, Znf292, Znf704*

Angiogenesis, Immune response

(3) F3, Tmem23, Vegfc

(1) Thbd

Development

(7) Bmp2, Bmp4, Id2, Inha, Inhbb, Kitl, Nog

(3) Bmf, Inhba, Mgp

Neurogenesis

-

(9) Apoe, Dscr1l1, Efna1, Gap43, Ntf5, Penk-rs, Plxnb1*, Pnoc, Rogdi*

Proteolysis, peptidolysis

(3) Gzmc, Lcn7, Prss23

(9) Adam10, Adam33*, Htra3*, Masp1, Plau, Plat, Plxnc1*, Tessp6, Ube2c

Others

(90) 37 predicted EST, 53 unknown EST

(74) 33 predicted EST, 41 unknown EST

Total

(176)

(170)