Table 4 Prevalence of various types of E. coli toxins and effectors among the IBD isolates
From: Comparative genomics of Escherichia coli isolated from patients with inflammatory bowel disease
Virulence factor | Pathotype | UC (5)a | CD (8)a | Nissle 1917 | CFT073 |
|---|---|---|---|---|---|
Shiga toxin I | EHEC | 0 | 0 | - | - |
Shiga toxin 2 | EHEC | 0 | 0 | - | - |
EHEC haemolysin (ehx) | EHEC | 0 | 0 | - | - |
Serine protease, EspP | EHEC | 0 | 0 | - | - |
Serine protease, EspC | EPEC | 0 | 0 | - | - |
Urease gene cluster | EHEC | 0 | 0 | - | - |
Cell-cycle inhibiting factor (cif) | EPEC, EHEC | 0 | 0 | - | - |
Type III secretion effector, Tir | EPEC, EHEC | 0 | 0 | - | - |
Type III secretion effector, EspF | EPEC, EHEC | 0 | 0 | - | - |
Type III secretion effector, EspH | EPEC, EHEC | 0 | 0 | - | - |
Inhibition of lymphocytes activation (Lif/Efa) | EPEC, EHEC | 0 | 0 | - | - |
Heat-labile enterotoxin (LT), alpha-subunit (eltA) | ETEC | 0 | 0 | - | - |
Type III secretion effector, IpaB | EIEC | 0 | 0 | - | - |
Shigella enterotoxin (ShET2) | EAEC, EIEC | 0 | 0 | - | - |
Haemolysin (hly) | ExPEC | 2 | 0 | - | + |
Cytotoxic necrotizing factor 1 (cnf1) | ExPEC, MNEC | 2 | 0 | - | - |
Serine protease, Sat | ExPEC | 4 | 2 | + | + |
Haemoglobin-binding protease (tsh) | ExPEC, APEC | 0 | 0 | - | -b |
Cytolethal distending toxin (cdt) | Several | 0 | 0 | - | - |