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Figure 3 | BMC Genomics

Figure 3

From: Implication of next-generation sequencing on association studies

Figure 3

Proportion of tagged SNPs and untaggable SNPs for the low coverage pilot and imputed dataset. We assumed the inter-marker distance to be 200 kb and calculated r2 between the tag SNP and all nearby SNPs within the distance, and then we plotted the proportions as a function of the r2 cut off values for the low coverage pilot dataset in A, B, C and D, and for the imputed CEU dataset in the regions of 382 genes covered by exon pilot project in E,F,G and H, respectively. A) Proportion of tagged common SNPs with 5% < MAF. B) Proportion of tagged low frequency SNPs with 0.5% < MAF ≤ 5%. C) Proportion of untaggable common SNPs with 5% < MAF. D) Proportion of untaggable low frequency SNPs with 0.5% < MAF ≤ 5%. E) Proportion of tagged common SNPs with 5% < MAF. F) Proportion of tagged low frequency SNPs with 0.5% < MAF ≤ 5%. G) Proportion of untaggable common SNPs with 5% < MAF. H) Proportion of untaggable low frequency SNPs with 0.5% < MAF ≤ 5%.

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