Figure 2

Profiles of histone modification H2BK5me1, H3K36me3 and H4K20me1 along pre-miRNA genomic sequence in CD4+ T cells. The y axis represents the mean value of histone modification coverage. Position zero on x axis corresponds to the center of pre-miRNA. (A) The occupancy profiles of H2K5me1 across a 2,000-nt window surrounding the centers of pre-miRNA genomic sequences corresponding to active-promoter miRNA, inactive-promoter miRNA, expressed miRNA and unexpressed miRNA (left) and those from their flanking regions (right). (B) The occupancy profiles of H3K36me3 across a 2,000-nt window surrounding the centers of pre-miRNA genomic sequences corresponding to active-promoter miRNA, inactive-promoter miRNA, expressed miRNA and unexpressed miRNA (left) and those from their flanking regions (right). (C) The occupancy profiles of H4K20me1 across a 2,000-nt window surrounding the centers of pre-miRNA genomic sequences corresponding to active-promoter miRNA, inactive-promoter miRNA, expressed miRNA and unexpressed miRNA (left) and those from their flanking regions (right).