Figure 3

Contents of GC, GC dinucleotides, AT, AT dinucleotides along pre-miRNA genomic sequence. Position zero on X axis corresponds to the center of pre-miRNA. (A) The GC (left) and AT (right) contents across a 2,000-nt window surrounding the center of pre-miRNA genomic sequence. (B) The GC dinucleotides (left) and AT dinucleotides (right) contents across a 2,000-nt window surrounding the center of pre-miRNA genomic sequence. (C) Nucleosome occupancy in a 2,000-nt window surrounding the center of pre-miRNA genomic sequence. The pre-miRNAs are divided into five equal bins (lowest, low, medium, high and highest) according to the GC content in a 400-nt window surrounding the center of pre-miRNA genomic sequence.