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Table 3 TFBSs that are present in all miRNA promoters in a particular (group of) cell type(s)

From: MicroRNA genes preferentially expressed in dendritic cells contain sites for conserved transcription factor binding motifs in their promoters

Cell types

Overrepresented TFBS

Monocytes

Elk-1, RREB-1, SPIB

DCs*

AP-4, E47, MAZR, Myf, MZF1, RREB1, RREB-1, Sp1, SPI1, SPIB, STAT6, ZNF42_1-4, ZNF42_5-13

Subset of DCs**

AP-1, ARP-1, FOXI1, myogenin/NF-1, Ncx, Oct-1, OCT-x, Sp1, TCF11, ZNF42_1-4

All cells***

Oct-1, RP58, SPIB, USF

  1. *) Includes monocyte-derived iDCs, maturing DCs, tolerogenic DCs and activated tolerogenic DCs
  2. **) Includes maturing DCs and/or activated tolerogenic DCs
  3. ***) Concerns all cells investigated, and miRNAs did not show appreciable differences in expression level
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BMC Genomics

ISSN: 1471-2164

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