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Table 3 Cell cycle distribution of MCF-7 cells prior to BaP treatment

From: Influence of cell cycle on responses of MCF-7 cells to benzo[a]pyrene

  

Cell cycle distribution (%)

Culture manipulations (time, h)

G0/G1-phase

S-phase

G2/M-phase

G0/G1-enriched

48 h serum deprivation

65.3 ± 2.1

14.1 ± 2.4

20.6 ± 2.4

S-enriched

18 h after 48 h serum deprivation

24.7 ± 4.2

55.7 ± 8.2

19.5 ± 4.0

G2/M-enriched

12 h colchicine (0.25 μM) after 24 h aphidicolin (1 μg/mL)

8.9 ± 2.2

18.2 ± 4.1

72.9 ± 5.9

  1. Cells were manipulated to generate: G0/G1-, S-, and G2/M-enriched cultures.