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Table 3 Aerobic and anaerobic gene pairs identified in the Cfl. aurantiacus genome

From: Complete genome sequence of the filamentous anoxygenic phototrophic bacterium Chloroflexus aurantiacus

(Putative) gene product and the EC number for aerobic and anaerobic gene product

Reaction catalyzed

Gene symbol and locus for aerobic genes

Gene symbol and locus for the anaerobic genes

Tetrapyrrole (heme, cobalamin and chlorophyll) biosynthesis

coproporphyrinogen III decarboxylase/oxidase - aerobic (EC 1.3.3.3) - anaerobic (EC 1.3.99.22)

convert coproporphyrinogen III to protoporphyrinogen IX in heme biosynthesis

hemF (Caur_2599)

hemN (Caur_0209, Caur_0644)

Mg-protoporphyrin IX monomethyl ester oxidative cyclase (EC 1.14.13.81)

the isocyclic ring formation in chlorophyll biosynthesis

acsF (Caur_2590)

bchE (Caur_3676)

cobalt chelatase - aerobic (EC 6.6.1.2) - anaerobic (EC 4.99.1.3)

cobalt insertion on the corrin ring in cobalamin biosynthesis

cobT (Caur_2578), cobN (Caur_2579) cobS (Caur_1198)

cbiK (Caur_2572)

Central carbon metabolism

α-ketoglutarate dehydrogenase E1 (EC 1.2.4.2), E2 (EC 2.3.1.61), and E3 (EC 1.8.1.4)

convert α-ketoglutarate to succinyl-CoA in the TCA cycle

E1 (sucA, Caur_3727) E2 (olst, Caur_1691, Caur_3726) E3 (dld, Caur_0170, Caur_2840)

 

α-ketoglutarate:ferredoxin oxidoreductase (or α-ketoglutarate synthase) (EC 1.2.7.3)

convert succinyl-CoA to α-keto-glutarate in the TCA cycle

 

korA (Caur_0249, Caur_0952) korB (Caur_0250, Caur_0953)

pyruvate dehydrogenase E1 (EC 1.2.4.1), E2 (EC 2.3.1.12), and E3 (EC 1.8.1.4)

convert pyruvate to acetyl-CoA in pyruvate metabolism

E1 (Caur_1334, 1335, 1972, 1973, 2805, 3121, 3671, and 3672), E2 (Caur_1333, Caur_1974), E3 (dld, Caur_0170, Caur_2840)

 

Central carbon metabolism

pyruvate:ferredoxin oxidoreductase (or pyruvate synthase) (EC 1.2.7.1)

convert acetyl-CoA to pyruvate in pyruvate metabolism

 

porA (Caur_0249, Caur_0952, Caur_2080)

Nucleic acid biosynthesis

ribonucleoside-diphosphate reductase aerobic (EC 1.17.4.1) anaerobic (EC 1.17.4.2)

convert ribonucleotide into deoxyribonucleotide in nucleic acids biosynthesis

nrdB (Caur_3331, β-subunit)

nrdJ (Caur_1750)

dihydroorotate oxidase (EC 1.3.3.1, aerobic), and dihydroorotate dehydrogenase (EC 1.3.99.11, anaerobic),

conversion of dihydroorotoate to orotate in pyrimidine biosynthesis

Caur_2081 and Caur_3923

Caur_2338