Figure 3

Quantity and mode of action of eQTL. eQTL were categorized as cis- or trans-acting based on map positions of the eQTL as compared to the genomic origin of the gene being measured by the microarray. A total of 10,941 eQTL were identified that were analyzable for mode of action based on strict transcript genomic origin criteria. Ninety per cent of all eQTL (9,795 of 10,941) functioned through a cis regulatory mechanism. Normalizing the number of eQTL identified as cis- or trans-shows that the stronger eQTL tend to function through cis-regulation (red, n = 9,795) while weaker eQTL tend to function through trans-regulation (blue, n = 1,146).