Table 1 Lists of unique genes contributing to the immune clusters
All clusters | Both NF-κB/Rel clusters | Both IRF/Stat1/Cutl1 clusters | Both disease clusters | Both GO clusters | NF-κB/Rel cluster (GO) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Gene | Hit rate | Gene | Hit rate | Gene | Hit rate | Gene | Hit rate | Gene | Hit rate | Gene | Hit rate |
HLA-A | 22.1% | TNF | 99.5% | TLR4 | 12.1% | HLA-B | 30.1% | CSF1 | 19.3% | ICAM1 | 74.7% |
NOD2 | 20.1% | LTA | 58.3% | IL6 | 9.5% | CARD15 | 22.3% | TNFSF13 | 13.3% | IRF6 | 44.0% |
STAT1 | 12.2% | TGFB1 | 36.9% | CTLA4 | 9.4% | VDR | 17.5% | FLT3LG | 8.0% | CD69 | 28.9% |
CD40 | 11.6% | CD4 | 24.8% | CCR5 | 8.5% | VEGF | 4.1% | RELB | 6.9% | REL | 27.7% |
TAP1 | 10.7% | AKT1 | 12.1% | TLR3 | 7.7% | NFKBIZ | 3.3% | CD27 | 6.0% | TNFRSF4 | 21.1% |
NFKBIA | 10.7% | LTB | 11.6% | HLA-DRB1 | 7.2% | COL6A1 | 2.4% | PER1 | 5.9% | RELA | 18.7% |
IRF1 | 10.1% | IL1RN | 10.2% | IL2 | 5.9% | PSORS1 | 2.1% | PTPN6 | 5.6% | EDC4 | 16.9% |
CXCL10 | 10.0% | IL2RA | 10.2% | IFNB1 | 4.2% | CYBA | 1.7% | LCK | 5.3% | CD58 | 14.5% |
IRF5 | 7.3% | TNFRSF1B | 5.3% | CCL2 | 4.1% | DDAH2 | 1.5% | MYD88 | 5.0% | TNFRSF18 | 14.1% |
PSMB8 | 6.7% | CD86 | 5.3% | TNFSF13B | 3.5% | CYP27B1 | 1.4% | PTMA | 4.8% | CD83 | 14.1% |
PSMB9 | 6.2% | ITGAM | 5.1% | MX1 | 3.3% | PLAU | 1.4% | IL27 | 4.7% | TNFRSF9 | 12.9% |
FAS | 5.5% | TRADD | 5.0% | STAT5A | 3.0% | RUNX1 | 1.3% | B2M | 4.3% | IL17C | 12.0% |
IL7R | 2.6% | MIF | 3.9% | NOD1 | 3.0% | RUNX3 | 1.2% | IRF2 | 3.1% | CD5 | 10.8% |
IFIH1 | 1.9% | NFKBIB | 3.4% | TLR1 | 2.9% | PAX2 | 1.1% | STAT3 | 3.0% | CD70 | 9.6% |
CXCL5 | 3.2% | HLA-DMA | 2.3% | CCND1 | 1.0% | TAPBP | 2.9% | DPP4 | 9.6% | ||
PTGS1 | 3.0% | CASP1 | 2.1% | RXRB | 1.0% | BIRC3 | 2.5% | NFATC2 | 9.0% | ||
SOCS1 | 1.7% | HIF1A | 0.8% | TRAF2 | 9.0% | ||||||
TRIM21 | 1.3% | CREB1 | 8.0% | ||||||||
CCL21 | 1.1% | ... | |||||||||