Table 5 Exon structure differences between female- and male- preferred transcript isoforms

Number of Genes

786

226

562

275

230

Median Length (bases)

240

21.5

196.5

99

544.5

362 Genes with Significant Ratios

5prime Exon

5prime Extension

Internal Exon

3prime Extension

3prime Exon

Number of Genes

157

49

120

64

36

P value*

0.18

0.43

0.43

0.18

0.018†

Median Length (bases)

194

18

157.5

155.5

725.5

P value⁺

0.012†

0.16

0.022†

0.17

0.043††

263 Genes with Significant Ratios downstream tra

5prime Exon

5prime Extension

Internal Exon

3prime Extension

3prime Exon

Number of Genes

118

36

92

50

26

P value*

0.43

0.48

0.21

0.088

0.03†

Median Length (bases)

206

17.5

153.5

467.5

725.5

P value⁺

0.094

0.35

0.026†

0.0029††

0.14

90 Genes with Robust Male Isoform Expression

5prime Exon

5prime Extension

Internal Exon

3prime Extension

3prime Exon

Number of Genes

35

14

25

24

8

P value*

0.11

0.29

0.19

0.0053††

0.13

Median Length (bases)

194

15.5

136

623.5

494.5

P value⁺

0.015†

0.45

0.17

0.00067††

0.46

42 Genes with Robust Female Isoform Expression

5prime Exon

5prime Extension

Internal Exon

3prime Extension

3prime Exon

Number of Genes

18

4

16

7

3

P value*

0.42

0.34

0.27

0.52

0.17

Median Length (bases)

224.5

45

180.5

9

3703

P value⁺

0.28

0.13

0.33

0.087

0.0056††