Table 1 Antibiotic susceptibility (mg/L) of B. cenocepacia J2315, resistant mutants and outbreak isolates
Antibiotic clasBs | Antibiotic name | wild type J2315 | J2315-A (AMKr) | J2315-M (MERr) | J2315-T (TMPr) | BCC 1616 | BCC 1617 |
|---|---|---|---|---|---|---|---|
Beta-lactams | Meropenem | 7 | 13 | 15 | 6 | 30 | 7 |
| Â | Imipenem | 125 | 125 | 175 | 100 | 175 | 100 |
| Â | Ceftazidime | 10 | 30 | 40 | 10 | 60 | 5 |
| Â | Cefotaxime | 250 | 500 | 1200 | 250 | >1500 | 15 |
| Â | Aztreonam | 250 | 500 | 1500 | 200 | >1500 | 40 |
| Â | Piperacillin | 450 | 450 | 900 | 350 | 1500 | 40 |
Aminoglycosides | Amikacin | 200 | 450 | 200 | 200 | 450 | 900 |
| Â | Gentamicin | 700 | 5000 | 450 | 400 | 10000 | >10000 |
| Â | Tobramycin | 150 | 500 | 300 | 125 | 1500 | 3000 |
Macrolides | Azithromycin | 50 | 40 | 40 | 30 | 200 | >500 |
| Â | Erythromycin | 150 | 150 | 200 | 150 | 500 | 800 |
Folate synthesis inhibitors | Trimethoprim/Sulfamethoxazole | 30/150 | 20/100 | 30/150 | 150/750 | 10/50 | 20/100 |
Fluoroquinolones | Ciprofloxacin | 7 | 7 | 8 | 30 | >50 | 13 |
| Â | Levofloxacin | 7 | 7 | 8 | 30 | >50 | 13 |
Rifamycins | Rifampicin | 90 | 70 | 100 | >200 | 60 | 80 |
Chloramphenicol | Chloramphenicol | 10 | 10 | 25 | >400 | 15 | 15 |
Tetracyclines | Tetracycline | 60 | 70 | 180 | 120 | 160 | >300 |