Circular genome representations. Circular representations of the available Brachyspira spp. genomes using DNAplotter. a, B. intermedia PWS/AT; b, B. hyodysenteriae WA1; c, B. murdochii 56-150T; d, B. pilosicoli 95/1000. The first two circles starting from the center in a-d are GC-skew and G+C content. The other eight circles starting after G+C content are circles showing genes conserved and shared in the four Brachyspira species: a, IHP, IMP, IHM, IP, IM, IH, I, IHMP; b, IHP, HMP, IHM, HP, HM, IH, H, IHMP; c, HMP, IMP, HIM, MP, MH, MI, M, IHMP; d, HMP, IMP, IHP, MP, HP,IP,P IHMP. The second circle from the outside shows all reverse strand genes. The outermost circle shows all forward strand genes in all four figures. The red- and green-colored genes are putative phage genes and putative virulence genes respectively.