A codon substitution model that incorporates the effect of the GC contents, the gene density and the density of CpG islands of human chromosomes

Table 1 Summary of data

Chromosome	GC Content (%)	Gene Density^a	CpG Island Density^a	Chromosome Size (base pair)	No. of genes used in this study	No. of codons used in this study
1	41.74	8.30	33.69	249250621	1123	504737
2	40.24	5.39	28.03	243199373	708	349066
3	39.69	5.68	18.20	198022430	644	311774
4	38.25	4.39	19.13	191154276	442	222017
5	39.52	5.24	24.77	180915260	521	266213
6	40.33	6.23	28.13	171115067	623	260600
7	40.75	6.45	42.13	159138663	472	214102
8	40.18	5.39	32.47	146364022	359	158173
9	41.31	5.94	35.58	141213431	420	192744
10	41.58	5.99	40.98	135534747	431	194136
11	41.57	10.24	38.98	135006516	593	255208
12	40.81	8.10	35.40	133851895	567	258243
13	38.53	2.95	23.29	115169878	198	100596
14	40.89	6.18	28.97	107349540	360	168500
15	42.20	6.91	29.00	102531392	321	165732
16	44.79	10.58	74.48	90354753	435	196533
17	45.54	15.48	81.09	81195210	549	246160
18	39.79	3.89	31.89	78077248	192	87095
19	48.34	25.28	134.13	59128983	525	205475
20	44.13	9.04	56.61	63025520	319	130636
21	40.84	5.17	44.32	48129895	127	54345
22	47.99	8.77	73.68	51304566	199	84980
X	39.50	5.62	19.66	155270560	244	90162

ISSN: 1471-2164