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Table 4 Involvement of PKA in the transcriptional regulation of different classes of genes controlled by glucose

From: Transcriptional responses to glucose in Saccharomyces cerevisiae strains lacking a functional protein kinase A

Class Transcriptional effect Glucose added to strain No glucose added Representative genes
   PKA+ PKA- PKA activated  
1 Induction + + - PFK1, ENO2
  Repression + + - CRC1, PCK1, MLS1
2 Induction + - + ARG3, THR4
  Repression + - + GRX2, PEP4
3 Induction + + + HXT3, RPL7A, HOR2
  Repression + + + ACS1, ADY2, CIT3
4 Induction + - - SDT1, STR3
  Repression + - - HXT6, MDH1
  1. The presence or absence of transcriptional response after addition of glucose to yeast strains with or without PKA activity is indicated by + or -. The column labelled "No glucose added" shows the transcriptional response when PKA is activated through an increase in cAMP that does not involve the presence of glucose [5].