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Table 1 Summary of the differentially expressed genes between T70 and U70 using IPA

From: Histological and transcriptome-wide level characteristics of fetal myofiber hyperplasia during the second half of gestation in Texel and Ujumqin sheep

Top Bio Functions

  

Diseases and Disorders

  

Name

p-value1

Molecules2

Cance r4

5.82E-08-.93E-03

51

Cardiovascular Disease 4

2.61E-06-7.93E-03

19

Developmental Disorder

2.61E-06-7.93E-03

12

Hypersensitivity Response

8.91E-06-7.93E-03

8

Inflammatory Response

1.05E-05-7.93E-03

25

Molecular and Cellular Functions

  

Name

p-value

Molecules

Cell-To-Cell Signaling and Interaction

1.77E-06-7.93E-03

32

Cellular Movement

8.91E-06-7.93E-03

25

Lipid Metabolism

9.16E-06-7.93E-03

25

Molecular Transport

9.16E-06-7.93E-03

28

Small Molecule Biochemistry

9.16E-06-7.93E-03

30

Physiological System Development and Function

  

Name

p-value

Molecules

Tissue Development

1.77E-06-7.93E-03

24

Hematological System Development and Function

7.13E-06-7.93E-03

22

Hematopoiesis

8.91E-06-7.93E-03

9

Immune Cell Trafficking

8.91E-06-7.93E-03

19

Skeletal and Muscular System Development and Function

2.68E-05-7.93E-03

18

Top Canonical Pathways

  

Name

p-value

Ratio 3

Acute Phase Response Signaling

2.2E-03

6/178 (0.034)

Glycolysis/Gluconeogenesis

7.65E-03

4/142 (0.028)

N-Glycan Biosynthesis

9.44E-03

3/93 (0.032)

Calcium Signaling

1.17E-02

5/204 (0.025)

CXCR4 Signaling

3.31-02

4/169 (0.024)

  1. 1. The p-value was calculated using a right-tailed Fisher's exact test. 2. The number of genes enriched in corresponding functions. 3. The ratio was calculated as the number of genes from our data set that overlap with the canonical pathway in question divided by the total number of genes represented in that canonical pathway.
  2. 4. Italicized terms such as "Cancer" and "Cardiovascular Disease" represent a biased annotation or are not related to the aim of the study.
  3. IPA version: 8.7 (release date: 09-17-2010)
  4. Content version: 3202 (release date: 07-07-2010)
  5. Reference set: Ingenuity knowledge base (genes only)
  6. Relationships to include: direct and indirect
  7. Includes endogenous chemicals
  8. Filter summary: Consider all molecules and/or relationships