Skip to main content


Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Figure 2 | BMC Genomics

Figure 2

From: The non-random clustering of non-synonymous substitutions and its relationship to evolutionary rate

Figure 2

Construction of the dispersion ratio. (a) The protein sequence of 27 amino acids in length introduced in Figure 1. (b) The pairwise alignment introduced in Figure 1. Sites a djacent to sites at which the amino acids are distinct are labeled with an "a"; the remaining sites are labeled "i" for i solated. This time, filled circles denote amino acid differences at adjacent sites, whereas the circles indicating amino acid differences at isolated sites are hollow. (c) The alignment is partitioned into its isolated and adjacent constituents, and the selection parameter ω is estimated for each (as ω I and ω A , respectively). The dispersion ratio ρ is computed as ω I /ω A .

Back to article page